Spatial Compartmentalization of the Microbiome between the Lumen and Crypts Is Lost in the Murine Cecum following the Process of Surgery, Including Overnight Fasting and Exposure to Antibiotics

ABSTRACT The cecum is a unique region in the mammalian intestinal tract in which the microbiome is localized to two compartments, the lumen and the crypts. The microbiome within crypts is particularly important as it is in direct contact with lining epithelial cells including stem cells. Here, we an...

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Detalhes bibliográficos

Principais autores:	Alexander Zaborin, Beatriz Penalver Bernabe, Robert Keskey, Naseer Sangwan, Sanjiv Hyoju, Neil Gottel, Jack A. Gilbert, Olga Zaborina, John C. Alverdy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2020-06-01
Colecção:	mSystems
Assuntos:	16S rRNA butyrate cecal crypts hypoxia gradient Mucispirillum schaedleri murine cecum microbiome
Acesso em linha:	https://journals.asm.org/doi/10.1128/mSystems.00377-20
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