Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts

<p>Abstract</p> <p>Background</p> <p>Simian Virus 40 (SV40) immortalization followed by treatment of cells with 3-methylcholanthrene (3-MC) has been used to elicit tumors in athymic mice. 3-MC carcinogenesis has been thoroughly studied, however gene-level interactions between 3-MC and SV40 that coul...

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Autors principals:	Easton Marilyn J, Yoon Lawrence W, George Michael, Moore Tanya M, Crosby Lynn M, Ni Hong, Morgan Kevin T, DeAngelo Anthony B
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2010-02-01
Col·lecció:	Cancer Cell International
Accés en línia:	http://www.cancerci.com/content/10/1/4
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