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Macrophage C/EBPδ Drives Gemcitabine, but Not 5-FU or Paclitaxel, Resistance of Pancreatic Cancer Cells in a Deoxycytidine-Dependent Manner

Treatment of pancreatic ductal adenocarcinoma (PDAC), a dismal disease with poor survival rates, is hampered by the high prevalence of chemotherapy resistance. Resistance is accompanied by macrophage infiltration into the tumor microenvironment, and infiltrated macrophages are key players in chemoth...

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Principais autores: C. Arnold Spek, Hella L. Aberson, JanWillem Duitman
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-01-01
Serija:Biomedicines
Teme:
Online dostop:https://www.mdpi.com/2227-9059/10/2/219
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