Tamoxifen Ameliorates Cholestatic Liver Fibrosis in Mice: Upregulation of TGFβ and IL6 Is a Potential Protective Mechanism

The available treatments for cholestatic liver fibrosis are limited, and the disease often progresses to liver cirrhosis. Tamoxifen is a selective modulator of estrogen receptors, commonly used in breast cancer therapy. A recent in vitro study showed that tamoxifen deactivates hepatic stellate cells...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Dino Šisl, Darja Flegar, Maša Filipović, Petra Turčić, Pavao Planinić, Alan Šućur, Nataša Kovačić, Danka Grčević, Tomislav Kelava
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2022-05-01
Reeks:	Biomedicines
Onderwerpen:	liver fibrosis tamoxifen DDC model cholestatic liver disease
Online toegang:	https://www.mdpi.com/2227-9059/10/5/1209
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!