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Efficacy and safety of a sustained-release formulation of ivermectin (FILAPREV®) in preventing heartworm infection (Dirofilaria immitis) in dogs in two endemic areas of Italy

Abstract Background Macrocyclic lactones are the only drug class currently licensed for heartworm disease prophylaxis. Macrocyclic lactones kill third- and fourth-stage larvae of the parasitic nematode Dirofilaria immitis, thus preventing the development of adult worms in dogs, which are responsible...

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Principais autores: Marco Genchi, Luigi Venco, Marta Fozzer, Alessia Crippa, Claudio N. Rossi, Laura Kramer, Alice Vismarra
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-05-01
Serier:Parasites & Vectors
Fag:
Dirofilaria immitis
Ivermectin
Implant
Slow release
Moxidectin
Heartworm prevention
Online adgang:https://doi.org/10.1186/s13071-026-07419-9
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