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Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules

Summary The mammalian cerebral cortex develops from proliferative apical progenitor cells (APs) that exhibit cell cycle-dependent nuclear movement (interkinetic nuclear migration; INM), which may be important for efficient and continuous production of neurons. The Pax6 transcription factor plays a m...

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Principais autores: Hiroshi Shinohara, Nobuyuki Sakayori, Masanori Takahashi, Noriko Osumi
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2013-06-01
Serija:Biology Open
Teme:
Online dostop:http://bio.biologists.org/content/2/7/739
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