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Treatment of lower-risk myelodysplastic syndromes

Myelodysplastic neoplasms (MDS) involve clonal hematopoiesis and cellular dysplasia, driven by genetic and epigenetic alterations. Spliceosome mutations and epigenetic dysregulation underscore the intricate pathogenesis of MDS. The bone marrow microenvironment, stromal dysfunction, chronic inflamma...

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Autori principali: Almuth Maria Anni Merz, Uwe Platzbecker
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2024-10-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/11799
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