Validation of a Microwave-Assisted Derivatization Gas Chromatography-Mass Spectrometry Method for the Quantification of 2-Hydroxybutyrate in Human Serum as an Early Marker of Diabetes Mellitus

Circulating levels of 2-hydroxybutyrate (2HB) are highly related to glycemic status in different metabolomic studies. According to recent evidence, 2HB is an early biomarker of the future development of dysglycemia and type 2 <i>diabetes mellitus</i> and may be causally related to the progression of...

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Detalhes bibliográficos

Principais autores:	María Rodríguez-García, Guillermo Fernández-Varo, Susana Hidalgo, Gabriela Rodríguez, Irene Martínez, Muling Zeng, Eudald Casals, Manuel Morales-Ruiz, Gregori Casals
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-03-01
coleção:	Molecules
Assuntos:	2-hydroxybutyrate microwave-assisted derivatization <i>diabetes mellitus</i> GC-MS TMS human serum
Acesso em linha:	https://www.mdpi.com/1420-3049/27/6/1889
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