Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells
<p>Abstract</p> <p>Background</p> <p>Stearoyl-CoA desaturase 1 (SCD1) is an ER resident enzyme introducing a double-bond in saturated fatty acids. Global knockout of SCD1 in mouse increases fatty acid oxidation and insulin sensitivity which makes the animal resistant to diet-induced obesity. Inhibit...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2010-09-01
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| Colecção: | Lipids in Health and Disease |
| Acesso em linha: | http://www.lipidworld.com/content/9/1/108 |
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