Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver-Resident Macrophage M2 Polarization via C/EBP Homologous Protein-Mediated Endoplasmic Reticulum Stress

Aggravated liver ischemia and reperfusion (IR) injury has been observed in hyperglycemic hosts, but its underlying mechanism remains undefined. Liver-resident macrophages (Kupffer cells, KCs) and endoplasmic reticulum (ER) stress play crucial roles in the pathogenesis of liver IR injury. In this stu...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Zhuqing Rao, Jie Sun, Xiongxiong Pan, Ziyang Chen, Heliang Sun, Panpan Zhang, Mei Gao, Zhengnian Ding, Cunming Liu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2017-10-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	liver ischemia and reperfusion hyperglycemia macrophage Kupffer cell endoplasmic reticulum stress C/EBP homologous protein
Онлайн хандалт:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01299/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!