Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperimmune sera
ABSTRACT The use of a commercial kit for the monocyte-activation test (MAT) was evaluated for assessing pyrogenic contamination of hyperimmune sera . Three batches of sera, two pyrogen free and one pyrogenic, were tested. Endotoxin spike recover indicated that sample dilutions from 1/2 to 1/10 are s...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2018-07-01
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| Schriftenreihe: | Brazilian Journal of Pharmaceutical Sciences |
| Schlagworte: | |
| Online-Zugang: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200605&lng=en&tlng=en |
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