CD248, targeted by veratramine and neobavaisoflavone, mediates pathological changes of renal tubular epithelial cells induced by high glucose

Abstract Background Epithelial-mesenchymal transition (EMT) of tubular epithelial cells are one of the major pathological changes of diabetic nephropathy (DN). Cluster of differentiation 248 (CD248) has been reported to be associated with fibrosis after kidney injury. The aim of this study was to in...

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Autors principals:	Mei Lin, Nan Hu, Zhen Wang, Ping Li, Dan Song, Xinzhou Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-12-01
Col·lecció:	Hereditas
Matèries:	Diabetic nephropathy CD248 TGF-β1/Smad pathway Veratramine Neobavaisoflavone
Accés en línia:	https://doi.org/10.1186/s41065-025-00624-z
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