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Unique Regulation of AQP1 and AQP5 Expression by HIF-1 in Nucleus Pulposus Cells

Introduction Aquaporins are a family of transmembrane water channels that aid in osmoregulation, a critical function in the proteoglycan-rich nucleus pulposus. Previous reports have demonstrated expression of aquaporins in the intervertebral disc. 1,2 Hypoxia, a defining feature of the nucleus pulpo...

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Bibliografiske detaljer
Principais autores: S. Gogate, Z. Johnson, R. Day, A. Binch, D. Markova, N. Chiverton, A. Cole, M. Conner, I. Shapiro, C. L. Le Maitre, M. Risbud
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2014-05-01
Serier:Global Spine Journal
Online adgang:https://doi.org/10.1055/s-0034-1376558
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