Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir

Cefdinir (CEF) is a semi-synthetic third-generation broad-spectrum oral cephalosporin that exhibits poor solubility at lower pH values. Considering this, pH-modulated CEF solid dispersions (ASDs) were produced by solvent evaporation method employing various hydrophilic carriers and alkalizers. Among...

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Bibliografski detalji

Glavni autori:	Yahya Alhamhoom, Thanusha Kumaraswamy, Avichal Kumar, Shivakumar Hagalavadi Nanjappa, Sanjana S. Prakash, Mohamed Rahamathulla, Kamal Y. Thajudeen, Mohammed Muqtader Ahmed, Thippeswamy Boreddy Shivanandappa
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-06-01
Serija:	Pharmaceutics
Teme:	cefdinir solid dispersion pH-modulated solubility antimicrobial activity
Online pristup:	https://www.mdpi.com/1999-4923/16/7/866
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