Curcuminoid Chalcones: Synthesis, Stability, and New Neuroprotective and Sonosensitising Activities

The primary purpose of this work was to design and obtain a series of curcuminoid chalcone–NSAID hybrid derivatives. The ester-type hybrid compounds with ibuprofen (<b>i</b>), ketoprofen (<b>ii</b>), and naproxen (<b>iii</b>) were obtained in two ways, using the Claisen–Schmidt reaction and the Steg...

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Bibliografiske detaljer

Principais autores:	Dorota Olender, Małgorzata Józkowiak, Hanna Piotrowska-Kempisty, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, Izabela Muszalska-Kolos, Ewa Baranowska-Wójcik, Dominik Szwajgier
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-09-01
Serier:	Pharmaceuticals
Fag:	curcuminoid chalcones hybrids NSAIDs Claisen–Schmidt reaction Steglich esterification reaction sonodynamic therapy
Online adgang:	https://www.mdpi.com/1424-8247/16/9/1331
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