Disruption of mitochondrial energy metabolism is a putative pathogenesis of Diamond-Blackfan anemia

Summary: Energy metabolism in the context of erythropoiesis and related diseases remains largely unexplored. Here, we developed a primary cell model by differentiating hematopoietic stem progenitor cells toward the erythroid lineage and suppressing the mitochondrial oxidative phosphorylation (OXPHOS...

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Detalhes bibliográficos

Principais autores:	Rudan Xiao, Lijuan Zhang, Zijuan Xin, Junwei Zhu, Qian Zhang, Guangmin Zheng, Siyun Chu, Jing Wu, Lu Zhang, Yang Wan, Xiaojuan Chen, Weiping Yuan, Zhaojun Zhang, Xiaofan Zhu, Xiangdong Fang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
coleção:	iScience
Assuntos:	Cellular physiology Cell biology Developmental biology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004224003936
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