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Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy

Abstract Prodrugs have been explored as an alternative to conventional chemotherapy; however, their target specificity remains limited. The tumor microenvironment harbors a range of microorganisms that potentially serve as tumor-targeting vectors for delivering prodrugs. In this study, we harness ba...

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Hlavní autoři: Haosheng Shen, Changyu Zhang, Shengjie Li, Yuanmei Liang, Li Ting Lee, Nikhil Aggarwal, Kwok Soon Wun, Jing Liu, Saravanan Prabhu Nadarajan, Cheng Weng, Hua Ling, Joshua K. Tay, De Yun Wang, Shao Q. Yao, In Young Hwang, Yung Seng Lee, Matthew Wook Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-05-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-024-48661-y
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