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Assembly landscape for the bacterial large ribosomal subunit

Abstract Assembly of ribosomes in bacteria is highly efficient, taking ~2-3 min, but this makes the abundance of assembly intermediates very low, which is a challenge for mechanistic understanding. Genetic perturbations of the assembly process create bottlenecks where intermediates accumulate, facil...

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Auteurs principaux: Kai Sheng, Ning Li, Jessica N. Rabuck-Gibbons, Xiyu Dong, Dmitry Lyumkis, James R. Williamson
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2023-08-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-023-40859-w
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