The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration.

The Hippo-YAP pathway responds to diverse environmental cues to manage tissue homeostasis, organ regeneration, tumorigenesis, and immunity. However, how phosphatase(s) directly target Yes-associated protein (YAP) and determine its physiological activity are still inconclusive. Here, we utilized an u...

全面介紹

書目詳細資料

Principais autores:	Ruyuan Zhou, Qirou Wu, Mengqiu Wang, Seema Irani, Xiao Li, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, Pinglong Xu
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2021-02-01
叢編:	PLoS Biology
在線閱讀:	https://doi.org/10.1371/journal.pbio.3001122
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!