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Exploring the Mechanism of Indigo Naturalis in the Treatment of Ulcerative Colitis Based on TLR4/MyD88/NF-κB Signaling Pathway and Gut Microbiota

Background: Clinical trials have proven that indigo naturalis is a candidate drug for treating ulcerative colitis (UC), but its therapeutic mechanism is still unclear.Purpose: This study aimed to evaluate the protective effect and mechanism of indigo naturalis to treat mice with dextran sulfate sodi...

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Principais autores: Qi-yue Yang, Le-le Ma, Chen Zhang, Jun-zhi Lin, Li Han, Ya-nan He, Chun-guang Xie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Pharmacology
Assuntos:
indigo naturalis
indigo
indirubin
ulcerative colitis
gut microbiota
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2021.674416/full
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