Urine L-selectin reflects clinical and histological renal disease activity and treatment response in lupus nephritis across multi-ethnicity

ObjectiveThere is an urgent need for novel biomarkers in lupus nephritis (LN). We report a non-invasive urinary biomarker, L-selectin, in two independent multi-ethnic cohorts.MethodsuL-selectin was tested cross-sectionally in a Chinese cohort (n=255) and a US cohort (n=219) of SLE patients and contr...

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Detalhes bibliográficos

Principais autores:	Yiwei Shen, Kamala Vanarsa, Zhihua Yin, Ting Zhang, Jessica Castillo, Min Dai, Linghua Zou, Ling Qin, Jieying Wang, Qiang Guo, Ramesh Saxena, Michelle Petri, Nan Shen, Zhizhong Ye, Chandra Mohan, Huihua Ding
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-08-01
coleção:	Frontiers in Immunology
Assuntos:	lupus nephritis L-selectin urinary biomarker renal histopathology treatment response
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1200167/full
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