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α-Glucosidase inhibitors boost gut immunity by inducing IgA responses in Peyer’s patches

Peyer’s patches (PPs) are specialized gut-associated lymphoid tissues that initiate follicular helper T (Tfh)-mediated immunoglobulin A (IgA) response to luminal antigens derived from commensal symbionts, pathobionts, and dietary sources. IgA-producing B cells migrate from PPs to the small intestina...

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Autori principali: Kisara Hattori-Muroi, Hanako Naganawa-Asaoka, Yuma Kabumoto, Kei Tsukamoto, Yosuke Fujisaki, Yumiko Fujimura, Seiga Komiyama, Yusuke Kinashi, Miki Kato, Shintaro Sato, Daisuke Takahashi, Koji Hase
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-11-01
Serie:Frontiers in Immunology
Soggetti:
follicular helper T cell
immunoglobulin A
peyer’s patch
α-glucosidase inhibitor
voglibose
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277637/full
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