Distinct neutralization sensitivity between adult and infant transmitted/founder HIV-1 subtype C viruses to broadly neutralizing monoclonal antibodies.

Broadly neutralizing antibodies (bnAbs), passively administered or elicited through vaccination, are a promising strategy for novel HIV prevention, treatment or inducing ART-free remission. However, HIV diversity and evolution are a barrier to the efficacy of bnAbs and there is therefore an urgent n...

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Bibliografische Detailangaben

Hauptverfasser:	Bongiwe Ndlovu, Kamini Gounder, Nelisiwe Zikhali, Lanish Singh, Ntokozo Ntshangase, Nombali Gumede, Jane Millar, Rebecca T van Dorsten, Nicholas E Grayson, David Bonsall, Sandra E Chaudron, Jennifer Mabuka, Krista L Dong, Bruce D Walker, Penny L Moore, Philip J R Goulder, Thumbi Ndung'u
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2025-06-01
Schriftenreihe:	PLoS Pathogens
Online-Zugang:	https://doi.org/10.1371/journal.ppat.1013245
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