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Epigenetically inactivated RASSF1A as a tumor biomarker

RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated by mutations, loss of heterozygosity, and, most commonly, by promoter hypermethylation. Epigenetic inactivation of RASSF1A...

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Principais autores: Dora Raos, Monika Ulamec, Ana Katusic Bojanac, Floriana Bulic-Jakus, Davor Jezek, Nino Sincic
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021-08-01
coleção:Biomolecules & Biomedicine
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Acesso em linha:https://www.bjbms.org/ojs/index.php/bjbms/article/view/5219
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