Upregulation of hepatic VLDLR via PPARα is required for the triglyceride-lowering effect of fenofibrate

The liver and the VLDL receptor (VLDLR) play major roles in TG and VLDL metabolism. However, the exact role of liver VLDLR is not well known because of the absence of or difficulty in detecting VLDLR in the liver. In this study, we demonstrate that fenofibrate, a PPARα agonist and widely used TG-low...

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Bibliografski detalji

Glavni autori:	Yang Gao, Wei Shen, Boyu Lu, Qingjiong Zhang, Yang Hu, Ying Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2014-08-01
Serija:	Journal of Lipid Research
Teme:	dyslipidemia very low density lipoprotein peroxisome proliferator-activated receptor α very low density lipoprotein receptor liver
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0022227520353268
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