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External Evaluation of Population Pharmacokinetics Models of Lithium in the Bipolar Population

Lithium has been used in the treatment of bipolar disorder for several decades. Treatment optimization is recommended for this drug, due to its narrow therapeutic range and a large pharmacokinetics (PK) variability. In addition to therapeutic drug monitoring, attempts have been made to predict indiv...

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Principais autores: Lereclus Aurélie, Boniffay Andréa, Kallée Gauvind, Blin Olivier, Belzeaux Raoul, Frédéric Dayan, Benito Sylvain, Guilhaumou Romain
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-11-01
Serier:Pharmaceuticals
Fag:
lithium
bipolar disorder
population pharmacokinetics
external evaluation
therapeutic drug monitoring
treatment optimization
Online adgang:https://www.mdpi.com/1424-8247/16/11/1627
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