Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities.
Erythropoietin (Epo)-induced Stat5 phosphorylation (p-Stat5) is essential for both basal erythropoiesis and for its acceleration during hypoxic stress. A key challenge lies in understanding how Stat5 signaling elicits distinct functions during basal and stress erythropoiesis. Here we asked whether t...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2012-08-01
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| Schriftenreihe: | PLoS Biology |
| Online-Zugang: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001383&type=printable |
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