Genome-informed metabolomic re-analysis identifies serum-associated amino acid signatures in sepsis-associated bacterial pathogens

BackgroundAntibiotic-resistant bacterial infections remain a major global health threat, particularly in hospital settings. Standard antimicrobial susceptibility testing provides essential clinical information, but it does not fully capture pathogen metabolic adaptation under host-like conditions. I...

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Principais autores:	Min Ou, Yulan Luo, Xiaopeng Sun, Shifeng Luo, Mei Feng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-06-01
coleção:	Frontiers in Medicine
Assuntos:	antibiotic response metabolomics multi-omics integration serum adaptation whole-genome sequencing
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1734675/full
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