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Regenerative potential of multinucleated cells: bone marrow adiponectin-positive multinucleated cells take the lead

Abstract Background Polyploid cells can be found in a wide evolutionary spectrum of organisms. These cells are assumed to be involved in tissue regeneration and resistance to stressors. Although the appearance of large multinucleated cells (LMCs) in long-term culture of bone marrow (BM) mesenchymal...

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Principais autores: Shiva Moein, Naser Ahmadbeigi, Rezvan Adibi, Sara Kamali, Kobra Moradzadeh, Pardis Nematollahi, Nance Beyer Nardi, Yousof Gheisari
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-07-01
Serier:Stem Cell Research & Therapy
Fag:
Bone marrow regeneration
Multinucleation
Irradiation
Adipocyte
Adiponectin
Hematopoiesis
Online adgang:https://doi.org/10.1186/s13287-023-03400-w
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