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A new mRNA antigen vaccine induces potent B and T cell responses and in vivo protection against SARS-CoV-2

Abstract The SARS-CoV-2 mRNA vaccine provides effective protection against viral infection and severe disease by inducing efficient adaptive immunity. However, vaccine efficacy is decreased against emerging variants, and immune memory is relatively short-lived. Here, we added new T cell epitopes to...

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Principais autores: Jing Wen, Jaesu Moon, Luca Tucciarone, Te-Hsuan Bu, Amanda Y. Sun, Robyn Miller, Julia Timis, Lujing Wu, Davey M. Smith, Sujan Shresta, Kyle J. Gaulton, Tariq M. Rana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2026-03-01
Serier:npj Vaccines
Online adgang:https://doi.org/10.1038/s41541-026-01421-z
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