Deciphering OCT4A-dose-dependent transcriptional profiles associated with tumorigenic potential in somatic cancer cells

Aims: The transcription factor OCT4A, a well-established master pluripotency factor, exerts regulatory effects on cell fate determination that are closely associated with its protein levels. This study aims to uncover the downstream gene profile features relevant to tumorigenic potential mediated by...

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Principais autores:	Min Tang, Rui Liang, Zhenyu Wu, Cheng Chen, Bo He, Ning Zhou, Sujuan Wang, Xinqiang Xiao, Guangdi Li, Yongfang Jiang, Guozhong Gong, Yanwen Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2026-01-01
Series:	SLAS Technology
Assuntos:	OCT4A Somatic cancer cell Transcriptional regulatory network Tumorigenicity RNA sequencing
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2472630325001402
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