Glutamine and cancer: metabolism, immune microenvironment, and therapeutic targets

Abstract Glutamine is the most abundant amino acid in human serum, and it can provide carbon and nitrogen for biosynthesis, which is crucial for proliferating cells. Moreover, it is widely known that glutamine metabolism is reprogrammed in cancer cells. Many cancer cells undergo metabolic reprogramm...

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Detalhes bibliográficos

Principais autores:	Ding Nan, Weiping Yao, Luanluan Huang, Ruiqi Liu, Xiaoyan Chen, Wenjie Xia, Hailong Sheng, Haibo Zhang, Xiaodong Liang, Yanwei Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-01-01
coleção:	Cell Communication and Signaling
Assuntos:	Glutamine metabolism Cancer Immune cells Glutamine antimetabolites Glutaminase inhibitors
Acesso em linha:	https://doi.org/10.1186/s12964-024-02018-6
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