Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses

The magnitude and duration of vertebrate viremia is a critical determinant of arbovirus transmission, geographic spread, and disease severity. We find that multiple alphaviruses, including chikungunya (CHIKV), Ross River (RRV), and o’nyong ‘nyong (ONNV) viruses, are cleared from the circulation of m...

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Detalhes bibliográficos

Principais autores:	Kathryn S Carpentier, Bennett J Davenport, Kelsey C Haist, Mary K McCarthy, Nicholas A May, Alexis Robison, Claudia Ruckert, Gregory D Ebel, Thomas E Morrison
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2019-10-01
coleção:	eLife
Assuntos:	arbovirus scavenger receptor innate immunity alphavirus
Acesso em linha:	https://elifesciences.org/articles/49163
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