Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study

Background Monocytes/macrophages participate in cardiovascular disease. CD163 (cluster of differentiation 163) is a monocyte/macrophage receptor, and the shed sCD163 (soluble CD163) reflects monocyte/macrophage activation. We examined the association of sCD163 with incident cardiovascular disease ev...

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Hauptverfasser:	Peter Durda, Laura M. Raffield, Ethan M. Lange, Nels C. Olson, Nancy Swords Jenny, Mary Cushman, Pia Deichgraeber, Niels Grarup, Anna Jonsson, Torben Hansen, Josyf C. Mychaleckyj, Bruce M. Psaty, Alex P. Reiner, Russell P. Tracy, Leslie A. Lange
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2022-11-01
Schriftenreihe:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Schlagworte:	cardiovascular diseases CD163 antigen genome‐wide association study humans monocytes risk factors
Online-Zugang:	https://www.ahajournals.org/doi/10.1161/JAHA.121.024374
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