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Investigating the STING Pathway to Explain Mechanisms of BCG Failures in Non-Muscle Invasive Bladder Cancer: Prognostic and Therapeutic Implications

Background: Intravesical Bacillus Calmette Guerin (BCG) has been the gold standard immunotherapy to treat high risk non-muscle invasive bladder cancer (NMIBC) for over 40 years. Attenuation of Mycobacterium bovis for clinical use as BCG results in loss of its ability to activate the “Stimulator of I...

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Principais autores: Madhuri Koti, Stephen Chenard, Sarah Nersesian, Thiago Vidotto, Alvaro Morales, D. Robert Siemens
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publishing 2019-11-01
Series:Bladder Cancer
Acceso en liña:https://doi.org/10.3233/BLC-190228
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