Lymph node-targeted neoantigen nanovaccines potentiate anti-tumor immune responses of post-surgical melanoma

Abstract Background Neoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and immunogenicity. Here, we developed a neoantigen nanovaccine used liposomes with lymph-node targeting characteristic. Methods Our nanovaccine was composed...

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Detalles Bibliográficos

Principais autores:	Yanhong Chu, Lingyu Qian, Yaohua Ke, Xiaoyu Feng, Xinjie Chen, Fangcen Liu, Lixia Yu, Lianru Zhang, Yaping Tao, Rui Xu, Jia Wei, Baorui Liu, Qin Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2022-04-01
Series:	Journal of Nanobiotechnology
Assuntos:	Neoantigen Cancer vaccine Nanoparticle Immunotherapy Anti-PD1 antibody
Acceso en liña:	https://doi.org/10.1186/s12951-022-01397-7
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