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Alterations in intestinal microbiota and metabolites in individuals with Down syndrome and their correlation with inflammation and behavior disorders in mice

The intestinal microbiota and fecal metabolome have been shown to play a vital role in human health, and can be affected by genetic and environmental factors. We found that individuals with Down syndrome (DS) had abnormal serum cytokine levels indicative of a pro-inflammatory environment. We investi...

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Uloženo v:
Hlavní autoři: Shaoli Cai, Jinxin Lin, Zhaolong Li, Songnian Liu, Zhihua Feng, Yangfan Zhang, Yanding Zhang, Jianzhong Huang, Qi Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-02-01
Edice:Frontiers in Microbiology
Témata:
Down syndrome
cytokines
intestinal microbiota
metabolomics
inflammation
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1016872/full
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