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Rapid detection of G6PD deficiency SNPs using a novel amplicon-based minion sequencing assay

Abstract Plasmodium vivax malaria remains a significant global health challenge, complicated by the parasite’s ability to form dormant liver stages (hypnozoites) that cause relapses. Radical cure of P. vivax malaria requires administration of a hypnozoitocidal drug, such as primaquine or tafenoquine...

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Bibliographic Details
Main Authors: Costanza Tacoli, Mariana Kleinecke, Kian Soon Hoon, Hidayat Trimarsanto, Muhammad Nadeem, Rotha Eam, Nimol Khim, Angela Rumaseb, Benedikt Ley, Dean Sayre, Sochea Phok, Dysoley Lek, Benoit Witkowski, Jimee Hwang, Sarah Auburn, Ivo Mueller, Ric N. Price, Jean Popovici
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2025-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-31822-4
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