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The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents.

<h4>Background</h4>QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific IFNγ-response. QFT reversion, also associated with low Tuberculin Skin Test r...

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Detalhes bibliográficos
Principais autores: Synne Jenum, Harleen M S Grewal, David A Hokey, John Kenneth, Mario Vaz, Timothy Mark Doherty, Frode Lars Jahnsen, TB Trials Study Group
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24992314/?tool=EBI
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