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Downregulation of trimethyl transferase SETD2 promotes migration and proliferation of colorectal cancer cell

Objective: To study the effect of histone H3 lysine 36 trimethyl transferase SETD2 on colorectal cancer (CRC) cells and the tumorigenesis. Methods: The expression of SETD2 mRNA and protein decreased in CRC cell HCT116 and SW480 with transference of short hairpin RNA. There were KD group and control...

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Autor principal: CUI Ang, DING Jiazeng, CHEN Haizhen, SHEN Xiaohui, LI Chaofei, LIU Guoliang
Format: Artigo
Idioma:Chinês
Publicat: Editorial Office of Journal of Surgery Concepts & Practice 2020-03-01
Col·lecció:Waike lilun yu shijian
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Accés en línia:https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1595690298719-1165289946.pdf
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