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Itpka depletion implicates defects in anterior neural development of Xenopus laevis

Inositol 1,4,5-trisphosphate 3-kinase A (Itpka) is a neuronal isoform of the ITPK family that regulates both actin dynamics and calcium signaling. While itpka deficiency in adult mice mainly results in central nervous system phenotypes, its contribution to early development remains unclear. To study...

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Bibliografiske detaljer
Principais autores: Ernestine Saumweber, Marie-Christine Becker, Sophie Kunkel, Jana Welke, Sandra Schott, Christian Vizinho-Vieira, Selina Faoual, Michael J. Schmeisser, Susanne J. Kühl
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-07-01
Serier:Frontiers in Cell and Developmental Biology
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Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2025.1610183/full
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