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Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in <it>Streptomyces ansochromogenes</it>

<p>Abstract</p> <p>Background</p> <p>Nikkomycins are a group of peptidyl nucleoside antibiotics and act as potent inhibitors of chitin synthases in fungi and insects. Nikkomycin X and Z are the main components produced by <it>Streptomyces ansochromogenes</it>. Of them, nikkomycin Z is a promising an...

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Bibliografiset tiedot
Päätekijät: Yang Haihua, Li Lei, Li Jine, Liao Guojian, Tian Yuqing, Tan Huarong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2009-11-01
Sarja:Microbial Cell Factories
Linkit:http://www.microbialcellfactories.com/content/8/1/61
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