HELIOS-expressing human CD8 T cells exhibit limited effector functions

IntroductionThe transcription factor HELIOS is primarily known for its expression in CD4 regulatory T cells, both in humans and mice. In mice, HELIOS is found in exhausted CD8 T cells. However, information on human HELIOS+ CD8 T cells is limited and conflicting. MethodsIn this study, we characterize...

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Bibliografiske detaljer

Principais autores:	Damien Neyens, Thibault Hirsch, Achraqat Abdel Aziz Issa Abdel Hadi, Nicolas Dauguet, Christophe Vanhaver, Alexandre Bayard, Claude Wildmann, Mathieu Luyckx, Jean-Luc Squifflet, Quentin D’Hondt, Céline Duhamel, Antoine Huaux, Virginie Montiel, Mélanie Dechamps, Pierre van der Bruggen
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2023-12-01
Serier:	Frontiers in Immunology
Fag:	HELIOS CD8 T lymphocytes Tc17 HLA-E human
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308539/full
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