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Bone marrow–derived emergency monopoiesis drives brain–lung axis injury after traumatic brain injury via IL-1

Abstract Traumatic brain injury (TBI) presents a major clinical burden, often resulting in both acute neurological impairment and pulmonary dysfunction, underscoring the complex and poorly understood brain–lung axis. Although dual-organ injury is well-documented, the mechanistic basis linking brain...

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Kaydedildi:
Asıl Yazarlar: Tianrui Ma, Jingjing Liu, Zhuyu Gao, Yang Li, Jie Lin, Kaifeng Pang, Rui Li, Xiaoyang Zhang, Lujia Tang, Yafan Liu, Hao Zhang, Yichi Zhang, Lorie Chen Cai, Zijian Zhou, Kaibin Shi, Tao Zhu, Jianning Zhang, Jieli Chen, Zhigang Cai, Ying Fu, Zilong Zhao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-11-01
Seri Bilgileri:Journal of Neuroinflammation
Konular:
Bone marrow
Interleukin-1
Monopoiesis
Traumatic brain injury
Lung injury
Online Erişim:https://doi.org/10.1186/s12974-025-03589-y
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