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Densest subgraph-based methods for protein-protein interaction hot spot prediction

Abstract Background Hot spots play an important role in protein binding analysis. The residue interaction network is a key point in hot spot prediction, and several graph theory-based methods have been proposed to detect hot spots. Although the existing methods can yield some interesting residues by...

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Autori principali: Ruiming Li, Jung-Yu Lee, Jinn-Moon Yang, Tatsuya Akutsu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-10-01
Serie:BMC Bioinformatics
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Accesso online:https://doi.org/10.1186/s12859-022-04996-1
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