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Cnr2 Is Important for Ribbon Synapse Maturation and Function in Hair Cells and Photoreceptors

The role of the cannabinoid receptor 2 (CNR2) is still poorly described in sensory epithelia. We found strong cnr2 expression in hair cells (HCs) of the inner ear and the lateral line (LL), a superficial sensory structure in fish. Next, we demonstrated that sensory synapses in HCs were severely pert...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Luis Colón-Cruz, Roberto Rodriguez-Morales, Alexis Santana-Cruz, Juan Cantres-Velez, Aranza Torrado-Tapias, Sheng-Jia Lin, Guillermo Yudowski, Robert Kensler, Bruno Marie, Shawn M. Burgess, Olivier Renaud, Gaurav K. Varshney, Martine Behra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-04-01
Schriftenreihe:Frontiers in Molecular Neuroscience
Schlagworte:
ribbon synapse
cannabinoid receptor 2
hair cells
inner ear
retina
photoreceptors 3
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnmol.2021.624265/full
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