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Eosinophil-Associated Innate IL-17 Response Promotes Aspergillus fumigatus Lung Pathology

Aspergillus fumigatus is a common widespread microorganism with environmental, biological and clinical relevance. After inhalation, swollen conidia can germinate, colonize and invade pulmonary tissues. Eosinophils have been described as key cells in A. fumigatus lung infection. However, their specif...

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Principais autores: Nathália Luísa Sousa de Oliveira Malacco, Milene Alvarenga Rachid, Isabella Luisa da Silva Gurgel, Tauany Rodrigues Moura, Pedro Henrique Ferreira Sucupira, Lirlândia Pires de Sousa, Daniele da Glória de Souza, Remo de Castro Russo, Mauro Martins Teixeira, Frederico Marianetti Soriani
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-01-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
Eosinophils role in inflammation
fungal infection
innate immunity
IL-17 innate response
eosinophil lung damage
Online adgang:https://www.frontiersin.org/article/10.3389/fcimb.2018.00453/full
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