The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2
Zhang et al. present the cryo-electron microscopy structures of the two neuronal cation-chloride cotransporters human NKCC1 and mouse KCC2, identifying their essential residues for ion transport. This study proposes mechanisms by which phosphorylation regulates the activity of these cation-chloride...
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| Autori principali: | , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2021-02-01
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| Serie: | Communications Biology |
| Accesso online: | https://doi.org/10.1038/s42003-021-01750-w |
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