Complement alternative pathway activation in human nonalcoholic steatohepatitis.

The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associat...

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Autors principals:	Filip M Segers, Froukje J Verdam, Charlotte de Jonge, Bas Boonen, Ann Driessen, Ronit Shiri-Sverdlov, Nicole D Bouvy, Jan Willem M Greve, Wim A Buurman, Sander S Rensen
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2014-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC4192551?pdf=render
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