Development and Clinical Indications of Cetuximab
Cetuximab is a chimeric immunoglobulin G1 monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR) with high specificity and affinity. It competitively inhibits endogenous ligand binding and thereby inhibits subsequent EGFR activation. The EGFR signali...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publishing
2007-01-01
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| Serier: | The International Journal of Biological Markers |
| Online adgang: | https://doi.org/10.1177/17246008070221s405 |
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